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Correspondence: J Du, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Anzhen Hospital, No. Tel: 86 10 64456030; Fax: 86 10 64451050; E-mail: [email protected] clearance of apoptotic cells (efferocytosis) can profoundly influence tumor-specific immunity.

In epidemiological studies, DNA methylation is the most frequent epigenetic mechanism studied because it can be measured in surrogate tissues in large populations in quantitative assays.

However, increased viewing of i CAM is strongly linked to increased ‘direct contact’ offending, as meeting and abusing victims online soon leads to meeting and abusing victims in person.

Since more and more people are viewing and building ‘i CAM libraries’, Safe Childhoods believes that a greater number of child sex offenders are emerging now than ever before.

Saliva samples were collected and methylation of promoter regions of four candidate genes or sequences (].

Obese children and adolescents may experience physical and psychological consequences, such as increased risk for the development of diabetes and cardiovascular diseases as well as low self-esteem [], a growing number of studies have investigated the role of epigenetic factors.

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Correspondence: Dr S Visvikis, Unité INSERM U525, 30 rue Lionnois, 54 000 Nancy, France.

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